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A weakness of our technique is
2024-08-28
A weakness of our technique is that during the early post-operative period without the scaffold of an enteric channel patients can be at risk for traumatic or difficult catheterization, with 3 of 6 requiring a visit. This appeared to be offset by having skilled and educated housestaff capable of rec
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(-)-Huperzine A br Funding br Introduction The interest in t
2024-08-28
Funding Introduction The interest in the effects of endocrine disrupting chemicals (EDCs) in the aquatic environment continues to increase over the past decade, specifically those that act on steroidogenic pathways. EDCs that include synthetic androgenic and estrogenic compounds can severely a
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br Conclusion br Acknowledgments This research has
2024-08-28
Conclusion Acknowledgments This research has been supported by the Ratchadaphiseksomphot Endowment Fund 2013 of Chulalongkorn University (CU-56-341-AS) and the Ratchadapiseksompotch Fund (RA55/22), Faculty of Medicine, Chulalongkorn University. The authors commemorate the 100th Anniversary of
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The Rv c EQ protein was
2024-08-28
The Rv2477c-EQ2 protein was purified from 600 ml induced cultures following the same protocol described above. Elution of the mutant protein from the affinity resin was done using 200 mM imidazole. After concentration and buffer-exchange of protein as described above, the purity of the protein was c
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The synthetic route for the
2024-08-28
The synthetic route for the aminobenzoxazole scaffold with a solvent accessible moiety is described in . Nitration of methoxyphenol and subsequent hydrogenation of the resulting nitro br 8 afforded compound . Aminobenzoxazole was formed by the reaction of compound with BrCN in EtOH. The solvent acce
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br Conflicts of interest br Financial support This work was
2024-08-28
Conflicts of interest Financial support This work was supported by grants from the Fondazione Cariplo [Grant number 2011-0463] (Carini); and by Funds for Original Research of the Università del Piemonte Orientale (2016, Project: Carini-Boldorini). The sponsors had no involvement in study desig
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Apelin is involved in various physiological functions includ
2024-08-28
Apelin is involved in various physiological functions, including N,N-Dimethylsphingosine receptor contraction (Ashley et al., 2005), vasodilatation (Jia et al., 2007), feeding control (Valle et al., 2008), and metabolic homeostasis (Higuchi et al., 2007, Dray et al., 2008, Attane et al., 2010). Its
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Phenolic compounds show reciprocal relationship with colonic
2024-08-28
Phenolic compounds show reciprocal relationship with colonic microflora. Phenolic compounds are able to improve colonic health and modulate microbiota diversity with prebiotic and antimicrobial functions, while colonic bacterial enzymes catalyze deconjugation, dehydroxylation, and convert phenolic c
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br Future directions outlook Peptide based
2024-08-28
Future directions-outlook Peptide-based macrocycles are among the privileged scaffolds in antibiotic drug discovery. Many compounds were discovered by natural product screening and developed unchanged, or as semi-synthetic derivatizations. Since the golden age of antibiotic discovery (1940s-mid 1
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As an internal control this
2024-08-28
As an internal control, this study validated many of the known associations between GATA3 and predictive markers. GATA3 was shown to be associated with ER and PR, which are both well-known correlations. GATA3 was also negatively correlated with nuclear grade, which is consistent with our knowledge o
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Plerixafor We found evidence of the interaction between AR
2024-08-27
We found evidence of the interaction between AR and hemiacetals by evaluating the effect of glucose on l-idose reduction. l-idose was recently proposed as the best AR substrate able to mimic glucose [38]. This aldose is structurally very closely related to d-glucose, from which it differs only in th
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HsALDH enzyme has been purified for the first
2024-08-27
HsALDH enzyme has been purified for the first time in our laboratory from human saliva and has been kinetically characterized using different aromatic substrates [35]. Also, the effect of some common substances frequently encountered by the enzyme in the oral cavity (such as ethanol, hydrogen peroxi
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br Preliminary remarks Expression of the transcription facto
2024-08-27
Preliminary remarks Expression of the transcription factor aryl hydrocarbon receptor (AHR) and the AHR-repressor (AHRR) are both strikingly high in the L-161,982 receptor of barrier organs skin and gut [1,2]. It is generally assumed that this reflects their role in linking environmental factors t
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A rate limiting step in the
2024-08-27
A rate-limiting step in the generation of kynurenine and xanthurenic prostaglandin receptor is the oxidation of N-formyl-kynurenine to l-kynurenine via indolamine 2,3-dioxygenase (IDO) or tryptophan dioxygenase (TDO). IDO and/or TDO knockdown decreases and ectopic over-expression increases producti
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Ambient levels of ppm ozone were
2024-08-27
Ambient levels of 0.2ppm ozone were recorded during a recent 2017 weather event in Texas, United States (EPA, 2007). This concentration or higher levels have been used in several human clinical studies during intermittent exercise (Miller et al., 2016c). Although ozone concentration of 0.8ppm used i
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