The findings of Qiu et al represent the

2019-08-24

The findings of Qiu et al. (2016) represent the first instance of a Ub-specific mono-ADP-ribosyltransferase, as well as the first documentation of E1/E2 independent ubiquitination. Post-translational modification of Ub certainly adds layers of complexity to our understanding of the Ub signal and should be taken into account for future investigations.

Does hydroxylation of proline have a specific

2019-08-23

Does hydroxylation of proline have a specific role in the structure and function of the conotoxins? Several studies in the literature provide insights into the role of proline hydroxylation in the Conus peptides.

Besides chemopreventive effects against oxidative DNA damage

2019-08-22

Besides chemopreventive effects against oxidative DNA damage we evaluated the protective effects of the three Hypericum sp. and isolated compounds against alkylating DNA damage induced by MMS in HT29 cells.

360A It is of interest to consider

2019-08-21

It is of interest to consider an explanation for the apparent phosphorylation of hSSB1 in undamaged cells.

The clinical management of patients with brain metastases is

2019-08-20

The clinical management of patients with BKM120 metastases is changed substantially in the last years, with a shift away from WBRT to SRS.

ER stress was monitored by both an increase

2019-08-19

ER stress was monitored by both an increase of the ER chaperone (GRP78, GRP94) and the activation of the ER resident caspase-12.

Mother rats acutely treated with quinpirole

2019-08-17

Mother rats acutely treated with quinpirole (0.5 and 1.0 mg/kg) decreased the pup exploration time but increased the object exploration, so they showed a significantly lower pup preference ratio.

Another important issue in biosensors is to design a

2019-08-16

Another important issue in biosensors is to design a simple and potable detection strategy to meet the requirement of the point-of-care (POC) test applications.

In many studies spatial and temporal expression and subcellu

2019-08-15

In many studies, spatial and temporal expression and subcellular localizations of the DNMTs are examined in greater detail.

By live imaging of GUL

2019-08-14

By live imaging of GUL-1-GFP, we observed the kinetics of aggregate movement within the cell.

Cellular immune responses such as

2019-08-13

Cellular immune responses, such as phagocytosis and apoptosis, are very important processes to eradicate the invading pathogens and reduce concomitant host damage. And all of these processes are fine-tuned by the ubiquitin system (Li et al., 2016).

Hello world!

2018-07-29